Synonyms: bFGF, FGF basic, FGF2, FGF-2, fibroblast growth factor 2 (basic), HBGF-2, Prostatropin

Accession: P09038

Description：FGF-2, also known as basic fibroblast growth factor, is a canonical FGF that belongs to the FGF-1 subfamily. It is a regulator of proliferation, migration, differentiation, cell survival, and stemness in human stem cells. More over，FGF-2 play a major role in skeletal development, bone formation, and fracture repair, which make FGF-2 an attractive molecule for clinical and pharmaceutical applications in bone regeneration.

Source: E.coli-derived human FGF basic/FGF2/bFGF protein, Pro143-Ser288.

Purity: ≥90% as determined by SDS-PAGE.

Endotoxin: < 1 EU per 1μg of the protein by the LAL method.

Predicted N terminal: Pro.

Molecular Mass: The recombinant human FGF basic/FGF2/bFGF consists of 146 amino acids and has a calculated molecular mass of 16.5 kDa.

Formulation: Supplied as sterile PBS, pH 7.4.

SDS-PAGE: 

The ED50 as determined by its ability to induce apoptosis using murine balb/c 3T3 cells is less than 1 ng/ml.

Handling: Centrifuge vial prior to opening.

Do not vortex after reconstitution.

Avoid repeated freeze-thaw cycles.

Reconstitution: Initially reconstitute in water to 0.1-1.0 mg/ml. Store at 2℃ to 8℃ for up to 1 week or prepare for extended storage.

Extended Storage: After initial reconstitution, further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA). Store working aliquots at -20℃ to 80℃.

Storage/Stability: