Synonyms: Interleukin-2; T-Cell Growth Factor; TCGF; Aldesleukin

Accession: P60568

Description：The human IL-2 protein, also known as interleukin-2, is an important cytokine that plays a vital role in regulating the immune system. It is produced by activated T cells and stimulates the proliferation and activation of various immune cells, such as T cells, B cells, and natural killer cells. IL-2 also promotes the development of immune memory and enhances the effectiveness of the immune response against infections and cancers. In addition, IL-2 has been used therapeutically in the treatment of certain diseases, such as cancer and autoimmune disorders, to boost the immune system.

Source: HEK293 cells-derived human IL-2 protein, Ala21-Thr153, with N-terminal his tag.

Purity: ≥90% as determined by SDS-PAGE.

Endotoxin: < 1 EU per 1μg of the protein by the LAL method.

Predicted N terminal: Met.

Molecular Mass: The recombinant human IL-2 consists of 140 amino acids and has a calculated molecular mass of 17.35 kDa.

Formulation: Supplied as sterile PBS, pH 7.4.

SDS-PAGE:

Human IL-2R immobilized on CM5 chip can bind human IL-2, His tag, with an affinity constant of 3.84 x 10^-7 M as determined in a SPR assay (Biacore 8K).

Handling: Centrifuge vial prior to opening.

Do not vortex after reconstitution.

Avoid repeated freeze-thaw cycles.

Reconstitution: Initially reconstitute in water to 0.1-1.0 mg/ml. Store at 2℃ to 8℃ for up to 1 week or prepare for extended storage.

Extended Storage: After initial reconstitution, further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA). Store working aliquots at -20℃ to 80℃.

Storage/Stability: